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Our studies reveal a new molecular glue that recruits its target protein directly to DDB1 to bypass the requirement of a substrate-specific receptor, presenting a new strategy for targeted protein degradation. Keywords: CDK12/CCNK; biochemistry; chemical biology; human; molecular glue; target identification; targeted protein degradation.
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On Feb. 10, 2022, Governor Steve Sisolak lifted the mask mandate. While the state will no longer require masks in public places, there are locations where Nevadans and visitors may still be asked to wear a mask. E mployers and organizations, including school districts, may set their own policies.
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